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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Why Is My Serum Beta-2 Microalbumin Level Always High?

yes I am a 55 year old female who was diagnosed with finely granular kidney cancer at the age of 45. I had a high urine beta 2 micro albumin test then and have had a continuously high serum beta 2 microalbumin level. what could be the cause of this? my serum creat level is always around 1.3
Wed, 15 Jul 2015
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General & Family Physician 's  Response
The kidneys filter wastes from the blood and reabsorb B2M. Because of this, only small amounts of B2M are normally present in the urine. If renal tubules in the kidneys become damaged or diseased, less is reabsorbed and concentrations of B2M in the urine increase.
In kidney disease, both blood and urine B2M tests may be ordered along with other kidney function tests such as BUN, creatinine, and microalbumin to evaluate kidney damage or disease and to distinguish between disorders that affect the glomeruli and the renal tubules.
This is not diagnostic but it is useful to monitor the treatment.
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Why Is My Serum Beta-2 Microalbumin Level Always High?

The kidneys filter wastes from the blood and reabsorb B2M. Because of this, only small amounts of B2M are normally present in the urine. If renal tubules in the kidneys become damaged or diseased, less is reabsorbed and concentrations of B2M in the urine increase. In kidney disease, both blood and urine B2M tests may be ordered along with other kidney function tests such as BUN, creatinine, and microalbumin to evaluate kidney damage or disease and to distinguish between disorders that affect the glomeruli and the renal tubules. This is not diagnostic but it is useful to monitor the treatment.