Hello, Thank you for trusting HCM. First its important that you get proper psychiatric counseling and management to your depression and pain. If that is already done, gaining weight has to be done using proper diet ( avoid fast food, sugar, etc.. ) but whole food, no capsules will magically add weight, plus training, resistance training lifting weights when done properly will make you stronger, help with the depression, sometimes even relief the period pain, plus will protect you from osteoporosis in the future, and will increase your appetite. There are high caloric supplements in the market but the quality of the gains are hard to control, and what you want is to add weight in a healthy way. Kind regards, Dr. Ahmad