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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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When Should I Take Second Injection Of HMG?

I have pcod my Dr. Advice me to take lupi. HMG 150 mg injection for 7th; 8th,and 9thday of my cycling .on 7thday I take injection at 3.00 pm .when will I take my 2nd injection day or night pls told me. I want to get pregnant so which is best for that injection pls answer me.
Tue, 30 Aug 2016
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General & Family Physician,  's  Response
Thanks for the query. No need to panic. There are 2 dosing therapies for administering HMG.
Two dosage schedules may be employed :
Schedule 1 : Alternate day therapy
Three equal doses of HMG are given on alternate days. In menstruating woman the initial dose of HMG should be given on day 7, 8 or 9 of the cycle. A single dose of HMG 10000 I.U. is given one week after the first injection of HMG, provided the clinical and biochemical responses are adequate and not excessive.
Schedule 2 : Daily therapy
Daily injections of HMG are given until an adequate response is achieved. This is judged on the basis of daily oestrogen determinations. In the absence of a response, the dose of HMG may be increased or the course abandoned. A single HMG injection of 10000 I.U. is administered 24 - 28 hours after the last dose of HMG. Schedule 2 is most commonly used.

Your doctor has prescribed schedule 1 and kindly re-confirm with your doctor on consultation immediately.
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When Should I Take Second Injection Of HMG?

Thanks for the query. No need to panic. There are 2 dosing therapies for administering HMG. Two dosage schedules may be employed : Schedule 1 : Alternate day therapy Three equal doses of HMG are given on alternate days. In menstruating woman the initial dose of HMG should be given on day 7, 8 or 9 of the cycle. A single dose of HMG 10000 I.U. is given one week after the first injection of HMG, provided the clinical and biochemical responses are adequate and not excessive. Schedule 2 : Daily therapy Daily injections of HMG are given until an adequate response is achieved. This is judged on the basis of daily oestrogen determinations. In the absence of a response, the dose of HMG may be increased or the course abandoned. A single HMG injection of 10000 I.U. is administered 24 - 28 hours after the last dose of HMG. Schedule 2 is most commonly used. Your doctor has prescribed schedule 1 and kindly re-confirm with your doctor on consultation immediately.