Hi, Yes, headache and wrist pain are important side effects of kingtropin. Kingtropin (human growth hormone) is commonly misused by athelete in an attempt to increase exercise capacity, improve bone density, build muscle mass, and reduce body fat. Its used is associated with a high risk for getting carpal tunnel syndrome (wrist pains), muscle, or joint pain, swelling of the arms and legs from fluid retention (edema), high cholesterol levels, high blood pressure, an increased risk of heart disease and diabetes, growth of facial features, hands, and feet (acromegaly), enlarged male breast, enlarged heart, and liver damage. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr. Mohammed Taher Ali