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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Is The Life Expectancy Of A Person With Acute Myeloid Leukemia?

My husband has Acute Myeloid Leukemia, 72, diagnosed October 2013. His CBC and DIFF lab numbers are very abnormal and he has been declining the last 4 months. Is it possible he is near end of life? He has had 25 chemo rounds and over 50 blood transfusion and platelets and labs are showing chemo is no longer working and is blasts are at 93%. He is very strong willed and I believe he is afraid to die because he is still somewhat in denial. He is not at peace. He has no religious affiliation. His oncologist keep prescribing but he is so ill. What can I do?
Tue, 15 Sep 2015
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General & Family Physician 's  Response
Hi,
Thanks for writing to HCM.
I understand your concern for your husband, who unfortunately has acute myeloid leukemia.
Acute myeloid leukemia (AML) is a type of blood cancer, which develops in the bone marrow from cells that would turn into white blood cells (other than lymphocytes).
I understand that he has already undergone and on appropriate treatment of chemotherapy and blood transfusion.
However, of all those with AML, around 20 out of 100 people (20%) will survive for 5 years or more after they are diagnosed. Younger people tend to do much better than older people.
Factors that affect outcome for AML and that it is harder to treat if:
1. Age is older (over 60)
2. High white blood cell count when diagnosed
3. AML developed from a condition called myelodysplasia or because of the treatment for another cancer
4. Particular genetic changes (mutations) in the leukaemia cells
5. It takes more than 2 cycles of chemotherapy to get leukaemia under control.
Hope the information provided would be clear.
Wish him good health.
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What Is The Life Expectancy Of A Person With Acute Myeloid Leukemia?

Hi, Thanks for writing to HCM. I understand your concern for your husband, who unfortunately has acute myeloid leukemia. Acute myeloid leukemia (AML) is a type of blood cancer, which develops in the bone marrow from cells that would turn into white blood cells (other than lymphocytes). I understand that he has already undergone and on appropriate treatment of chemotherapy and blood transfusion. However, of all those with AML, around 20 out of 100 people (20%) will survive for 5 years or more after they are diagnosed. Younger people tend to do much better than older people. Factors that affect outcome for AML and that it is harder to treat if: 1. Age is older (over 60) 2. High white blood cell count when diagnosed 3. AML developed from a condition called myelodysplasia or because of the treatment for another cancer 4. Particular genetic changes (mutations) in the leukaemia cells 5. It takes more than 2 cycles of chemotherapy to get leukaemia under control. Hope the information provided would be clear. Wish him good health.