Low hemoglobin/Anemia describes the condition in which the number of red blood cells in the blood is low. causes of anemia may be classified as impaired red blood cell (RBC) production, increased RBC destruction , blood loss and fluid overload. Several of these may interplay to eventually cause anemia. Indeed, the most common cause of anemia is blood loss, but this usually doesn t cause any lasting symptoms unless a relatively impaired RBC production develops, most commonly by iron deficiency. Anemia of renal failure, Anemia of endocrine disorders Disturbance of proliferation and maturation of RBC Pernicious anemia is due to vitamin B12 deficiency dependent on impaired absorption of vitamin B12. o Anemia of folic acid deficiency with vitamin B12, it causes megaloblastic anemia o Iron deficiency anemia, resulting in deficient heme synthesis o Anemia of renal failure Hemolytic anemia Anemias of increased red blood cell destruction are generally classified as hemolytic anemias. It can be idiopathic, that is, without any known cause, drug-associated or secondary to another diseases Blood loss * Trauma or surgery, causing acute blood loss * Gastrointestinal tract lesions, causing a rather chronic blood loss * Gynecologic disturbances, also generally causing chronic blood loss * Anemia of pregnancy is anemia Disclaimer