Hello. I read your question carefully and try to answer it to the best of my possibilities. The MRI report indicates narrowing of your small blood vessels, leading to some of them being blocked and causing these small foci which are tiny brain areas damaged by not receiving blood by these blocked vessels. Their significance depends however also on your age and possible diseases. If your age is advanced then this type of damage is a common finding. They are favored by conditions like hypertension, diabetes, smoking, obesity and blood lipid abnormalities and the best way to limit this vessel narrowing process is to address the above-mentioned conditions. If you are young and don t have any of those risk factors then you should be looked into for a long list of other possible reasons like metabolic disorders some of which inherited, connective tissue disease, inflammatory and autoimmune diseases etc. Hope to have answered your question. Feel free to come back for further inquiries.