Hi, High levels of chromium in the blood can indicate exposure to excessive amounts of this metal. Chromium is used in various industrial processes and can be found in some products, such as leather, paints, and cement. However, in your case, the high levels of chromium in your blood are likely due to the metal-on-metal hip resurfacing. Metal on metal hip implants can release small particles of metal into the body, including chromium. In some cases, this can cause an immune reaction that leads to inflammation, tissue damage, and an increased risk of developing cancer, including NHL. In your case, the high levels of chromium in your blood may be a result of the hip resurfacing procedure. However, it is also possible that other factors may be contributing to the development of the NHL. If your clinical trial is successful in achieving remission of NHL, it is important to continue monitoring your chromium levels to ensure they do not continue to increase. Your healthcare provider may also recommend additional measures to minimize your exposure to chromium, such as avoiding certain products or environments that contain this metal. It is also important to note that the relationship between chromium exposure and NHL is still being studied and understood. Your healthcare provider can provide you with more information on your specific situation and any potential risks or concerns related to high chromium levels in your blood. If you require a personalized response, kindly use the Ask A Doctor service and post a follow-up. Take care. Hope I have answered your question. Regards, Dr. Priyanka, General & Family Physician