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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does Follicular Epithelial Lesion In Culture Test Suggest?

Age: 51, female, 5'2" ht, 45 kgs. Thyroid problem since an year. Now FNAC was done. Here are the results. Does it look like cancer? Wat should be the approach? Can a general surgeon do the surgery for this?Microscopic appearance/FNAC Biopsy:SMEARS SHOW AGAINST A BACKGROUND OF SCANTY COLLOID ADD MIXED WITH BLOOD, MONOLAYER CLUSTERS OF FOLLICULAR EPITHELEAL CELLS WITH FOCI OF NUCLEAR ENLARGEMENT AND PLEOMORPHISM.Some follicular structure are also seen.A few cells resembling hurthle cells are seen.Impression:FOLLICULAR EPITHILEAL LESION,? GOITRE,? FOLLICULAR NEOPLASM.High resolution thyroid sonography:Diffuse enlargement of both lobes of the thyroid gland seen with intact capsule and no significant increase in vascularity.No evidence of any focal lesion made out.Right lobe measures 6.0 X 3.6 X 3.3 cm.Left lobe measures 5.8 X 3.1 X 2.3 cm.Isthmus is enlarged in size and normal shape and texture measures 9.9 mm in thickness.Common carotid arteries on both size are normal.Tracheal shadow is normal.
Tue, 26 Aug 2014
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Pathologist and Microbiologist,  's  Response
Hi,
Thanks for asking.
Based on your clinical history and query, my opinion is as follows:
1. FNAC of the lesion shows a certain foci of nuclear enlargement and pleomorphism which are indicators for a neoplasm. Does not necessarily indicate cancer, it can be benign or malignant. However these features are seen in goitre (enlarged thyroid).
2. FNAC is inconclusive in such a scenario. Next course of action would be biopsy study. You can discuss with your consulting doctor regarding thyroidectomy.
3. Yes, a general surgeon can do the surgery.
Hope it helps.
Any further queries, happy to help again.
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What Does Follicular Epithelial Lesion In Culture Test Suggest?

Hi, Thanks for asking. Based on your clinical history and query, my opinion is as follows: 1. FNAC of the lesion shows a certain foci of nuclear enlargement and pleomorphism which are indicators for a neoplasm. Does not necessarily indicate cancer, it can be benign or malignant. However these features are seen in goitre (enlarged thyroid). 2. FNAC is inconclusive in such a scenario. Next course of action would be biopsy study. You can discuss with your consulting doctor regarding thyroidectomy. 3. Yes, a general surgeon can do the surgery. Hope it helps. Any further queries, happy to help again.