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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Could Be The Reason For Decreasing INR While Being On Coumadin?

Hi. I'm Al and I was hospitalized in September for 10 days for multiple PE's in my legs and lungs. My INR during the past month has been 3,2, and yesterday 1.8. My doctor upped my coumadin from 3.75 for only 2 days a week and 7.5 for the other 5. Is there a reason why the INR keeps dropping? Thanks
Fri, 26 Sep 2014
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Hematologist,  's  Response
Hi, dear.
I have gone through your question. I can understand your concern.
In case of pulmonary embolism you should maintain your inr between 2 to 3. Effect of warferrin is decreased in your body. So we have to increase dose to maintain the level of INR. There are many causes for reduced the effect of warferrin. You may have some drugs or due to metabolic effect or due to resistance. So just need to increase the dosage. Go for repeat inr test after a month.
Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using health care magic.
Wish you a very good health.
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What Could Be The Reason For Decreasing INR While Being On Coumadin?

Hi, dear. I have gone through your question. I can understand your concern. In case of pulmonary embolism you should maintain your inr between 2 to 3. Effect of warferrin is decreased in your body. So we have to increase dose to maintain the level of INR. There are many causes for reduced the effect of warferrin. You may have some drugs or due to metabolic effect or due to resistance. So just need to increase the dosage. Go for repeat inr test after a month. Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using health care magic. Wish you a very good health.