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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes White Spots Post A Phenehren Injection?

My mother was given a phenehren injection. Immediately after the injection a white spot with a red and black ring came up. Shortly after the center turned black. Now 2 days later she has a nickle size white spot with a red edge. There is no drainage but seems to be hard under skin. What could this be?
Thu, 29 Sep 2016
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General & Family Physician 's  Response
Phenergan Injection can cause severe chemical irritation and damage to tissues regardless of the route of administration. Irritation and damage can result from perivascular extravasation, unintentional intra-arterial injection, and intraneuronal or perineuronal infiltration. Adverse reactions include burning, pain, thrombophlebitis, tissue necrosis, and gangrene. In some cases, surgical intervention, including fasciotomy, skin graft, and/or amputation have been required
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What Causes White Spots Post A Phenehren Injection?

Phenergan Injection can cause severe chemical irritation and damage to tissues regardless of the route of administration. Irritation and damage can result from perivascular extravasation, unintentional intra-arterial injection, and intraneuronal or perineuronal infiltration. Adverse reactions include burning, pain, thrombophlebitis, tissue necrosis, and gangrene. In some cases, surgical intervention, including fasciotomy, skin graft, and/or amputation have been required