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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Variations In Blood Test Levels While On Prednisone?

Hi, My husband has been in intensive care with possible sarcoidosis .We are now home his oxygen levels are 92% and he has just had a blood test and has elevated white cell count of 27 ,crp of 1 and elevated neutro . He s on 30mg of prednisone. He is very quiet and sometimes he s wheezy and says his chest feels sometimes tight . Do you feel that the steroids are altering his blood or does he need antibiotics .He is allergic to penicillin. He has has an echo cardiogram and all is well . Any help will be great
Fri, 15 Apr 2016
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General & Family Physician,  's  Response
Hello dear
Understand your concern.
Steroid causes increase in leucocyte mostly polymorph leucocyte count called leucocytosis.
It generally occur after 2 week after treatment.
It is due to delayed migration of leucocyte into tissue,
Delyed death of neutrophil
and release of new neutophil from the bone marrow.
But there is no toxic granulation that is present in the infection.

So do not woory it is not infection , it is side effcects of steroids on CBC.

Hope this may help you
Best regards
Dr. Sagar
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What Causes Variations In Blood Test Levels While On Prednisone?

Hello dear Understand your concern. Steroid causes increase in leucocyte mostly polymorph leucocyte count called leucocytosis. It generally occur after 2 week after treatment. It is due to delayed migration of leucocyte into tissue, Delyed death of neutrophil and release of new neutophil from the bone marrow. But there is no toxic granulation that is present in the infection. So do not woory it is not infection , it is side effcects of steroids on CBC. Hope this may help you Best regards Dr. Sagar