Thank you,doc. I have been taking 2.5 mg bid Norvasc (amylodipine) for 15 years.I am 69 and in good health. Recently though, I have developed swelling on my left ankle and calf and slight pain on my right calf with pain down from my hip to my ankle.i did have numbness and tingling for two months but that has settled.i am active,on my feet a lot doing gardening and walking. My bp is normal. I weigh 145 lbs. I also take 2.5 mg Cipralex for anxiety. I feel very positive and energised about my life. Thank you.