Thank you. My mother is 90 and has the beginning stages of Alzheimer's. She has a pain in her thigh, X-ray and MRI showed nothing. Drs say it is a muscle knot and ordered physical therapy and 5 mg Oxycodone. It wasn't helping, so they increased the dose to 10mg, 3-4 times a day. She insists that nothing is helping. She says she is in pain even with the medication, which is very strong! She sounds more confused and forgetful than usual, we think due to the medication, but I am concerned about 2 things: Can the oxycodone make her Alzheimer's symptoms worse, even after she stops taking them? And Could it be her Alzheimer's that makes her feel like she is pain even with the strong medication? Thank you for your help.