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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Severe Pain In The Feet And Legs Despite Taking Gabapentin?

I have been having severe pain in my feet and legs. I am a diebetic and been dianosed with nurophopy. I saw dr. salles in tullohoma for the first time and let him know of the pain i have been going through .i have been on gabapentin 600 mg. three times a day .He told there was no change in my condition from the last time i was there when Dr Capps was was there and to keep taking the medicine I was perscriped.That dianosis did not help my pain. Can you suggest my next step?
Fri, 10 Mar 2017
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Diabetologist 's  Response
Hello,

Welcome to Healthcare Magic.

I have read your question fully and understand your concerns.
Instead of gabapentin, you could try Pregabalin. Start with 75 mg once a day and then increase it to 75 mg twice a day. Based on pain relief, you could increase the dose up to a maximum of 300 mg twice a day. As you have tolerated gabapentin well, you should not find much difficulty in tolerating Pregabalin too.

Another option is Amitriptyline; you could start at the smallest dose of 10 mg at bed time. Based on pain control, gradually increase to 50 mg at night. If you are still able to tolerate without side effects, you could go up to maximum of 75 mg at night. Side effects from Amitriptyline are dry mouth, sedation, gastric upset, light headedness etc. Many people are able to tolerate lower doses well.

Both the tablets are prescription only medications, hence you would need to see a doctor for the prescription.

I hope this answer has helped you.

Thank you

Regards
Dr Sunita Sayammagaru
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What Causes Severe Pain In The Feet And Legs Despite Taking Gabapentin?

Hello, Welcome to Healthcare Magic. I have read your question fully and understand your concerns. Instead of gabapentin, you could try Pregabalin. Start with 75 mg once a day and then increase it to 75 mg twice a day. Based on pain relief, you could increase the dose up to a maximum of 300 mg twice a day. As you have tolerated gabapentin well, you should not find much difficulty in tolerating Pregabalin too. Another option is Amitriptyline; you could start at the smallest dose of 10 mg at bed time. Based on pain control, gradually increase to 50 mg at night. If you are still able to tolerate without side effects, you could go up to maximum of 75 mg at night. Side effects from Amitriptyline are dry mouth, sedation, gastric upset, light headedness etc. Many people are able to tolerate lower doses well. Both the tablets are prescription only medications, hence you would need to see a doctor for the prescription. I hope this answer has helped you. Thank you Regards Dr Sunita Sayammagaru