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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Rise In Transaminase And LDH Levels In Blood?

Hello, I would be very grateful if you answer to me. What could be the cause of increased transaminases and LDH in the blood. The results of blood analysis of my sister are as follows: transaminase 240, LDH has a value of 540th.
Kind regards,
Ranko Milicevic, Belgrade, Serbia
                                                           
Mon, 19 Jan 2015
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Pathologist and Microbiologist,  's  Response
Hello and welcome to HCM,
Rise of transaminase and LDH levels in blood suggests liver related problem.
Transaminase levels rise in cases of injury to liver cells or hepatocytes.
LDH enzyme has various iso-enzymes which increase in diseases of liver, heart and brain.
Rise in LDH along with rise in transaminases suggests that there is some disease process in liver.
Liver function tests are required to know the status of other enzymes like alkaline phosphatase, gamma GT and 5-nucleotidase.
Cause of elevated transaninases will be determined after assessing all liver unction tests.

Thanks and take care
Dr Shailja Puri
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What Causes Rise In Transaminase And LDH Levels In Blood?

Hello and welcome to HCM, Rise of transaminase and LDH levels in blood suggests liver related problem. Transaminase levels rise in cases of injury to liver cells or hepatocytes. LDH enzyme has various iso-enzymes which increase in diseases of liver, heart and brain. Rise in LDH along with rise in transaminases suggests that there is some disease process in liver. Liver function tests are required to know the status of other enzymes like alkaline phosphatase, gamma GT and 5-nucleotidase. Cause of elevated transaninases will be determined after assessing all liver unction tests. Thanks and take care Dr Shailja Puri