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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Persistent Elevation In Platelet Count Of A Toddler?

My 3 year old has been generally unwell for 5 months with random spikes in fever, episodes of vomiting, pink eye, ear infections, and pain in legs. During a follow-up doctors visit some bloodwork was done to see how the latest round of steroids and antibiotic were doing to fight the pink eye and ear infection. Her blood work showed high level of wbc (22.3), neutrophils (16.6), monocytes (1.7), and platelets (582), and glucose serum (34). Because her labs were so abnormal she had them repeated at the hospital a week later and a week post steroid/antibiotic, where they were still abnormal. Finally, her labs were repeated a week after the last abnormal labs (2 weeks post steroid/antibiotic) and the wbc,neutrophils, and glucose were all in normal range BUT her platelets are 575 and monocytes are 1.7. We are very concerned that the high platelet count is virtually unchanged and seem to indicate an issue with bone marrow. Could this be some type of cancer?
Tue, 15 Mar 2016
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Pathologist and Microbiologist 's  Response
Hello and welcome to HCM,
High platelet count is commonly seen accompanying infections.
Your history shows that your child is suffering from couple of infections.
These infections have led to increase in platelet count.
With the control of infections with antibiotics, the infection is controlled.
The platelet count will also subsequently come down, however, it is not indicative of bone marrow disorder or any type of cancer.
You may repeat the blood test after a month to monitor the level of platelets.

Thanks and take care
Dr Shailja Puri
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What Causes Persistent Elevation In Platelet Count Of A Toddler?

Hello and welcome to HCM, High platelet count is commonly seen accompanying infections. Your history shows that your child is suffering from couple of infections. These infections have led to increase in platelet count. With the control of infections with antibiotics, the infection is controlled. The platelet count will also subsequently come down, however, it is not indicative of bone marrow disorder or any type of cancer. You may repeat the blood test after a month to monitor the level of platelets. Thanks and take care Dr Shailja Puri