Am male 36 yrs old. Have had a chronic problem with anal itching, burning and sometimes bleeding which was brought to doctors attention about 6 months ago. Was told they thought i had a anal fissue , and were unable to do a digital anal exam at the time due to pain. Was given nitroglycerin cream and wipes to use which helped. Was also started on vitamin D supplements as my blood showed a deficiency. Since then i have lost approx 40 lbs without dieting, anal problems having started giving me problems again, and all the fingers on my hands are pruning up and at times the skin is peeling on them.