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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Persistent UTI Despite Taking Antibiotics Along With Muscle Weakness?

I ve been taking levofloxacin since last Monday night, two a day, for a stubborn uti that I have been fighting for two months.. Five courses of antibiotics since first of December. I am eighty one am pretty careful to be clean, have a pessarythat doesn t stay put but ordered one hat hopefully will and think that contributes to problem maybe. I have been pretty sick before starting this new course, cannot tolerate Cipro. My appatite s zero am trying to hydrate.b. I. HURT! I hurt pretty bad all over before Monday, everywhere for other reasons and still do but in last days muscles especially in upper arms and shoulders hurt to move, first one side, now both. The muscles are weak so even picking up half a glass of water is hard and painful. I have three and a half Days left at two a day, 500m. The last prescription I got was this same kind but only one a day for five days, there was three weeks seemed better between that last and this time. What is happening? Please advise. My M.D. Is Mitch Jenkins, Island of Kauai, Hawaii. Help please. Thanks, Mary
Thu, 17 Mar 2016
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General & Family Physician,  's  Response

Hello dear,
Recurrent UTIs are symptomatic UTIs that follow resolution of an earlier episode, usually after appropriate treatment.
Recurrent UTIs include relapses (i.e., symptomatic recurrent UTIs with the same organism following adequate therapy) and UTI caused by a second bacterial isolate)

Causative factor:
E. coli, Staphylococcus saprophyticus (10 to 15 percent). Enterococcus, Klebsiella, Enterobacter, and Proteus
Diabetes mellitus, neurologic conditions, chronic institutional residence,

Treatment are below
1. three day course of trimethoprim/sulfamethoxazole (TMPSMX; Bactrim, Septra) is the current standard therapy,
2. with three days of trimethoprim or a fluoroquinolone (i.e., ofloxacin, norfloxacin [Noroxin], or ciprofloxacin [Cipro]) being equally effective.

3. Fluoroquinolones and nitrofurantoin become better options in your case for TMP-SMX resistance increases.

4.If oral drug is not possible, take ceftazidime parentrally.
You should shift to oral therapy with in 72 hr as you able to tolerate oral drugs.
Follow up urine culture after 14 days to confirm the eradication of bacteria.

Take plenty of water
Tablet Paracetamol 500 mg thrre times a day if fever is present.
Hope this advice help you..
Thank you.
Get well soon.
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What Causes Persistent UTI Despite Taking Antibiotics Along With Muscle Weakness?

Hello dear, Recurrent UTIs are symptomatic UTIs that follow resolution of an earlier episode, usually after appropriate treatment. Recurrent UTIs include relapses (i.e., symptomatic recurrent UTIs with the same organism following adequate therapy) and UTI caused by a second bacterial isolate) Causative factor: E. coli, Staphylococcus saprophyticus (10 to 15 percent). Enterococcus, Klebsiella, Enterobacter, and Proteus Diabetes mellitus, neurologic conditions, chronic institutional residence, Treatment are below 1. three day course of trimethoprim/sulfamethoxazole (TMPSMX; Bactrim, Septra) is the current standard therapy, 2. with three days of trimethoprim or a fluoroquinolone (i.e., ofloxacin, norfloxacin [Noroxin], or ciprofloxacin [Cipro]) being equally effective. 3. Fluoroquinolones and nitrofurantoin become better options in your case for TMP-SMX resistance increases. 4.If oral drug is not possible, take ceftazidime parentrally. You should shift to oral therapy with in 72 hr as you able to tolerate oral drugs. Follow up urine culture after 14 days to confirm the eradication of bacteria. Take plenty of water Tablet Paracetamol 500 mg thrre times a day if fever is present. Hope this advice help you.. Thank you. Get well soon.