Hi, Clindamycin may rarely lower the respiratory capacity of the patient, particularly when combined with other drugs that may have the same side effect (like amikacin for example). With clindamycin alone, it s a rather rare effect occurring in less than 1% of patients. A low respiratory rate or low oxygen saturation may prove that her complaint is an objective one (not a subjective one). I suppose you don t have an oximeter at home but your doctor should have one. You can count her respiratory moves though. The normal rate is 14-20 per minute. If it s lower than that then perhaps she s indeed affected by clindamycine. Hope I have answered your query. Let me know if I can assist you further.