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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Low INR Values While On Warfarin Tablet?

Im on warfarin ,mi inr is low..i haven t missed a dosage at all never...they keep adjusting the medication...but im on warfarin since March 2015 ..i had a pulmonary embolism at that time...im concern...i been diagnose with factor 8..,is that the cause of my inr is low...
Tue, 21 Apr 2020
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General & Family Physician,  's  Response
Hi,

Could be an inadequate dose of warfarin. Warfarin is an oral anticoagulant which acts by decreasing the production of vitamin K-dependent coagulation factors 2,7,9,10, proteins C and S.

It does not decrease factor-8. Low INR is indicative of an inadequate warfarin dose which means blood clots will not be prevented.

Consult your doctor to adjust the dose of warfarin in a such a way to have the INR target of 2.5. This range is appropriate for the prevention of venous thromboembolism.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr. Mohammed Taher Ali
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What Causes Low INR Values While On Warfarin Tablet?

Hi, Could be an inadequate dose of warfarin. Warfarin is an oral anticoagulant which acts by decreasing the production of vitamin K-dependent coagulation factors 2,7,9,10, proteins C and S. It does not decrease factor-8. Low INR is indicative of an inadequate warfarin dose which means blood clots will not be prevented. Consult your doctor to adjust the dose of warfarin in a such a way to have the INR target of 2.5. This range is appropriate for the prevention of venous thromboembolism. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr. Mohammed Taher Ali