Hi thanks for asking question. Enlarge liver could be by infection , cancer or hemolytic anemia... Your doctor has done your physical examination.So he might have suspected cancer and let s see report of CT scan... Another possibility if cancer not present could be hepatitis ...If need viral marker may needed. It could be by chronic hemolysis also ex.thalessemia, autoimmune hemolysis , drug induce hemolysis, g6 PD deficiency etc. For hemolysis primary work up us with peripheral smear examination and retic count... If still exact cause not clear USG guided biopsy done for final approach... Hope your concern solved.... Take care. Dr.Parth