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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Increase To BP, Decrease In Pulse Rate After Started Bystolic?

My Doctor has given me a brand new medicine sample named as Bystolic ( 5mg Nebivolol) for HIgh BP. but in three days my BP has gone up from 150 to 190 dys. and pulse rate has gone down from 57 to 41. Should I discontinue or not. Have you heard of this new medicine?
Fri, 4 Apr 2014
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General & Family Physician 's  Response
Hi!
I read carefully your query!

Nebivolol is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension
Nebivolol slows down the activity of your heart by stopping messages sent by some nerves to your heart.That's the reason why your pulse rate has gone down.
Nebivolol also relaxes (widens) some blood vessels. These two things together allow the pressure of blood within your blood vessels to be reduced and make it easier for your heart to pump blood around your body.
Sometimes when you start a new medication to treat hypertension it takes some time to get the right effect.So I think you have to give it some time(maybe 10 days) and monitor your blood pressure during this time.
It is very important you follow any dietary and lifestyle advice that you may have been given by your doctor, such as eating a healthy diet, not smoking, and taking regular exercise.
If after you have done this your blood pressure is still high you need to consult your doctor so he will prescribe you something else to control your BP.

Treatment with nebivolol is usually long-term so continue to take these tablets unless your doctor tells you to stop. Stopping treatment suddenly can cause problems in some people, so your doctor will probably want you to reduce your dose gradually if this is necessary.

Take care.

Dr.Rovena
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What Causes Increase To BP, Decrease In Pulse Rate After Started Bystolic?

Hi! I read carefully your query! Nebivolol is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension Nebivolol slows down the activity of your heart by stopping messages sent by some nerves to your heart.That s the reason why your pulse rate has gone down. Nebivolol also relaxes (widens) some blood vessels. These two things together allow the pressure of blood within your blood vessels to be reduced and make it easier for your heart to pump blood around your body. Sometimes when you start a new medication to treat hypertension it takes some time to get the right effect.So I think you have to give it some time(maybe 10 days) and monitor your blood pressure during this time. It is very important you follow any dietary and lifestyle advice that you may have been given by your doctor, such as eating a healthy diet, not smoking, and taking regular exercise. If after you have done this your blood pressure is still high you need to consult your doctor so he will prescribe you something else to control your BP. Treatment with nebivolol is usually long-term so continue to take these tablets unless your doctor tells you to stop. Stopping treatment suddenly can cause problems in some people, so your doctor will probably want you to reduce your dose gradually if this is necessary. Take care. Dr.Rovena