Hello dear. Thanh you for using hcm. Treatment of impetigo typically involves local wound care along with antibiotic therapy. Antibiotic therapy for impetigo may be with a topical agent alone or a combination of systemic and topical agents. Gentle cleansing, removal of the honey-colored crusts of nonbullous impetigo using antibacterial soap and a washcloth, and frequent application of wet dressings to areas affected by lesions are recommended. Good hygiene with antibacterial washes, such as chlorhexidine or sodium hypochlorite baths, may prevent the transmission of impetigo and prevent recurrences, but the efficacy of this has not been proven. Beta-lactam drugs remain an appropriate initial empiric choice for systemic antibiotics for the treatment of impetigo. This includes penicillin derivatives , cephalosporins , monobactams, and carbapenems. There is no evidence that retinol cream could breakout them. Best regards.