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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Headaches While On Lamictal And Topamax?

I am taking 200 MG of Lamictal twice a day, 100 mg. Topamax at bedtime and now I just started 50 mg of Seroquel. I have had headaches for several days. I understand that Seroquel is a antidepressant drug. A long time ago, I was only on a fibermyalgic drug that was used for my manic disorder by my primary and I was hospitalized. I am concerned. My psychiatrist had me on Lamictal 200 mg., Topmax 50 mg. and Zyprexa since 2011. He had me go off the Zyprexa completely. It took me 2 weeks to wean myself off. He tried 2 days of Depakote and I had real bad head pain. He told me if the Seroquel does not agree with me because of the headaches to go back on the Zyprexa - not even telling me to take one or 2 tablets of 2.5 mg. at night..... I had to specifically ask his secretary. I feel good more alert on the antidepressant but just researched it tonight and realized what it was. He never asked me if I could take this type of medicine. I went off the Zyprexa because I believed it put me in a manic spending state that was a near financial disaster since 2011 when he put me on it. I have to stay with him until I have another doctor. My question is to you. Should I stay on the Seroquel a few more days and see if I still have head pain and then go back on the Zyprexa? What are your thoughts?
Fri, 21 Sep 2018
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Internal Medicine Specialist 's  Response
Hello,

Seroquel and Zyprexa both are antipsychotic drugs. Both can be used for a psychotic headache and other mood changes.

If you're feeling better with Zyprexa you can continue it no problem. But you can consult once your neuropsychiatrist he will examine and treat you accordingly.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Penchila Prasad Kandikattu , Internal Medicine Specialist
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What Causes Headaches While On Lamictal And Topamax?

Hello, Seroquel and Zyprexa both are antipsychotic drugs. Both can be used for a psychotic headache and other mood changes. If you re feeling better with Zyprexa you can continue it no problem. But you can consult once your neuropsychiatrist he will examine and treat you accordingly. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Penchila Prasad Kandikattu , Internal Medicine Specialist