Hello, Thankyou for asking your queation at health caremagic. If a patient comes to me with these symptoms I would want a more detailed history first Pattern of fever pattern of joint pain and when did it start?How long does the pain last when did the cough with sputum begin?Any blood in sputum History of swollen lymph glands in the body Any vision changes, red or watery eye Any change in bowel habits/Urinary symptoms Any similar history in past and past medical history History of any infections in the past. Any similar history in family Places visited recently, history of camping , history of tick bite (lyme disease can present with joint pain,fever and tiredness) All these questions are looking for the possibility of inflammatory disorders. Since you are complaining of weight loss, joint pain ,tiredness , cough I am encouraging possibility of inflammatory disorders (especially Sarcoidosis) We also need more investigations done like Complete Blood count, hemoglobin ESR , CRP Rheumatoid Factor, ACCP, ANA Chest X ray Urine analysis,Urine culture Renal function test And more investigations may also be warranted depending on your deatailed history and results of initial investigations. Meanwhile there are certain life style changes that can help you with your symptoms and energy level Diet rich in fruits and vegetables Making sure to get enough sleep Even though it is difficult, try doing mild exercise like slow walking everyday Ibuprofen 600mg twice daily (if not allergic to ) for pain I recommend that you consult your primary care physician or rheumatologist as soon as possible to get the work up done. Hope I was able to answer your question. Regards, Lekshmi