Hello, The doctor has updated and given me new plans to select instead of the current one that (40 mg Prozac daily along with 150 mg Wellbutrin XL daily) which I have used to treat GAD and SAD , Note that I have started treatment from GAD and SAD since 2007 with SSRIs, and Note that I can not do without medications to control the GAD because when I stopping the medication I getting relapse. PLEASE, can you lead me which one the best accordingly to your experiences If I would like to control GAD and avoid the current side effects that I suffer from as much as we can which it is (Fatigue, weight gain, somnolence and tremor or shaking in hands) and along with premature ejaculation and get good erection : Option 1: Replaced the current medications I use (40 mg Prozac daily along with 150 mg Wellbutrin XL daily) with Effexor XR 150 mg daily, but we hesitate because of weight gain, increase the pressure and harm the liver which related to Effexor maybe.. what do you think about that please ?? Option 2 : Replaced the current medications with Buspar 15 mg 3 times daily along with 150 mg Wellbutrin XL daily.. what about weight gain and fatigue about Buspar ? What the reality of Buspar ? is it ZERO effect ?? What do you think about this option please ? Option 3 : Replace the current medications with Buspar 15 mg 3 times daily along with 20 mg Prozac ?? here weight gain, your opinion ??? Thank you very much. Best Regards Arman