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What Causes Dizziness And Numbness In The Feet?
I ve recently had some test done and 8 of them came out not so good. HDL 50L ATL 41H white blood cell count 11.0 H hemoglobin 15.8H hematocrit 47.1H ACTH,plasma 60H dhea sulfate 522H testosterone /lc/ms/ms 63H. I m dizzy all the time have really bad headaches can t control my hands from shaking and my feet and hands and legs go numb all day long. I can t think clearly and get fevers a lot. I can t seem to lose weight even if I run 3 to 6 miles a day. My whole body is breaking out in acne and I m losing my hair. And none of this started happening until after I had my son. I also have what they call a buffalo hump on the back of my neck, all my weight is in the mid body and upper body my legs are a size 5 and my stomach is a size 13 please help me
Tue, 26 Jun 2018
Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.
Acne, truncal obesity, buffalo humps, high DHEAS and increased adrenocorticotropic hormone (ACTH) are suggestive of central hypercortisolism – mainly Cushing's disease. It is overproduction of adrenal hormones in the body. Adrenal gland hormone (cortisole) level in the body is mainly controlled by ACTH from pituitary gland. High ACTH directs adrenal glands to produce more cortisol which causes rounded face, acne, increased fat around the neck, truncal obesity, fatigue, weakness, high blood pressure, etc. Besides pituitary gland ACTH may also be produced by other pathologic tissues in the body.
You should have a test called high dose dexamethasone suppression test. If after the administration of high dose dexamethasone ACTH production suppresses it shows pituitary problem (mainly hormone producing from pituitary adenoma - Cushing's disease). If high dose dexamethasone cannot suppress ACTH production it means ACTH production from a tissue other than pituitary gland (very rare).
Please, consult with your doctor about Cushing's disease and high dose dexamethasone suppression test.
Hope I have answered your query. Let me know if I can assist you further.
Thank you,
Malik Amonov MD
I have reviewed your query and here is my advice.
Acne, truncal obesity, buffalo humps, high DHEAS and increased adrenocorticotropic hormone (ACTH) are suggestive of central hypercortisolism – mainly Cushing's disease. It is overproduction of adrenal hormones in the body. Adrenal gland hormone (cortisole) level in the body is mainly controlled by ACTH from pituitary gland. High ACTH directs adrenal glands to produce more cortisol which causes rounded face, acne, increased fat around the neck, truncal obesity, fatigue, weakness, high blood pressure, etc. Besides pituitary gland ACTH may also be produced by other pathologic tissues in the body.
You should have a test called high dose dexamethasone suppression test. If after the administration of high dose dexamethasone ACTH production suppresses it shows pituitary problem (mainly hormone producing from pituitary adenoma - Cushing's disease). If high dose dexamethasone cannot suppress ACTH production it means ACTH production from a tissue other than pituitary gland (very rare).
Please, consult with your doctor about Cushing's disease and high dose dexamethasone suppression test.
Hope I have answered your query. Let me know if I can assist you further.
Thank you,
Malik Amonov MD
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