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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Depression Inspite Of Taking Lamictal And Wellburtin?

My 55 y.o. brother has major depression. He s taking prescribed Lithium & Abilify & Effexor. Dr tried to wean from Lithium since he s been on it for many yrs, but depression got much worse. Dr added Lamictal & Wellbutrin recently & his symptoms significantly improved, but as soon as he weaned from Effexor, he feels quite depressed again. Why can t Wellbutrin & Effexor be taken together?
Mon, 9 Nov 2015
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General & Family Physician 's  Response
HI, thanks for using healthcare magic

Effexor increases the toxicity of welbutrin by an unknown mechanism and this has the potential to cause very serious side effects.
Can cause potentially life threatening reactions.

I hope this helps
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What Causes Depression Inspite Of Taking Lamictal And Wellburtin?

HI, thanks for using healthcare magic Effexor increases the toxicity of welbutrin by an unknown mechanism and this has the potential to cause very serious side effects. Can cause potentially life threatening reactions. I hope this helps