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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Bronchitis After Taking Methotrexate For Arthritis?

I am 66, and have psoriatic arthritis and have developed bronchitis which I feel was brought on from taking methotrexate tablets. These were stopped after 10 weeks as I had nausea and GI pain. The Consultant started me on sulfasalazine 500mg tablets 5 days ago. Should I tell him I now have bronchitis? and how do I look after myself now? Thanks
Thu, 11 Aug 2016
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Pulmonologist,  's  Response
Methotrexate is given as an immuno-modulator drug for rheumatoid arthritis. but it carried a adverse effect of causing lung fibrosis in a few patients and at times its quite difficult that this lung fibrosis has been caused by Rheumatoid arthritis or by its treatment with methotrexate.So It is called an Interstitial lung disease then. Bronchitis is usually a feature of methotrexate adverse effect. the bronchitis you have developed needs further evaluation to know what caused it. and also is it acute bronchitis or a chronic bronchitis?
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What Causes Bronchitis After Taking Methotrexate For Arthritis?

Methotrexate is given as an immuno-modulator drug for rheumatoid arthritis. but it carried a adverse effect of causing lung fibrosis in a few patients and at times its quite difficult that this lung fibrosis has been caused by Rheumatoid arthritis or by its treatment with methotrexate.So It is called an Interstitial lung disease then. Bronchitis is usually a feature of methotrexate adverse effect. the bronchitis you have developed needs further evaluation to know what caused it. and also is it acute bronchitis or a chronic bronchitis?