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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes An Unusual Feeling While On Pristiq And Cymbalta?

Hi there my name is Gianna. I was recently put on Pristiq 50mg only in the morning. I also was put on Cymbalta 60mg Am. & Pm. One of them is making me sick. My Neurologist I saw this morning he told me that I cannot take the Pristiq with the Cymbalta, that’s why I was having some side effects but my pharmacy didn’t catch that. I stopped the Pristiq after 3 days because that Doctor was on vacation. Can you help me out with this?
Wed, 12 Sep 2018
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Neurologist,  's  Response
Hi,

Can you specify your question since it seems that you are already aware your neurologist has recommended you not take Pristiq with Cymbalta due to drug to drug interactions? It is true that these 2 medications taken together could cause symptoms of serotonin excess and feeling "sick" or nauseous is certainly one possible symptom.

You should check with the prescribing physician to discuss alternative medications since this combination doesn't seem to be working for you.

Hope I have answered your query. Let me know if I can assist you further.
Regards,
Dr. Dariush Saghafi, Neurologist
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What Causes An Unusual Feeling While On Pristiq And Cymbalta?

Hi, Can you specify your question since it seems that you are already aware your neurologist has recommended you not take Pristiq with Cymbalta due to drug to drug interactions? It is true that these 2 medications taken together could cause symptoms of serotonin excess and feeling sick or nauseous is certainly one possible symptom. You should check with the prescribing physician to discuss alternative medications since this combination doesn t seem to be working for you. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Dariush Saghafi, Neurologist