Dear Ma am, Hi I can understand your concern regarding the possible interactions between green leafy vegetables or grapefruit juice with Acenocumarol. 1. Acenocumarol is an anticoagulant ( blood thinner ) used in the treatment & prevention of thromboembolic diseases (blood clot related complications) like transient ischemic attack (TIA), cerebral embolism, deep vein thrombosis, pulmonary embolism, etc. 2. Acenocumarol prevents clot formation by interfering with Vitamin K-dependent clotting factors. The highest concentrations of Vitamin K are found in green leafy vegetables such as collards, spinach, turnip greens, Brussels sprouts, broccoli, scallions, asparagus, and endive. Eating too much green leafy vegetables, therefore can decrease the ability of Acenocumarol to prevent clotting. If you decrease your intake of Vitamin K (by reducing the intake of green leafy vegetables) your dose of Acenocumarol may need to be lowered to prevent bleeding. Similarly, if you increase your intake of Vitamin K, your dose of Acenocumarol may need to be increased to prevent blood clots. So, you don t have to avoid foods that are high in vitamin K, just keep your diet consistent. 3. Grapefruit juice when taken along with Acenocumarol can inhibits its metabolism thus causing a slight increase in your international normalization ratio (INR, which is a measure of how long it takes your blood to clot). So again, it s best not to drink grapefruit juice regularly if you are taking Acenocumarol. 4. Besides, too much alcohol, cranberry products, or grapefruit products can increase Acenocumarol’s effect and increase your risk of bleeding. Therefore, avoid or limit your intake of alcohol, cranberry products, and grapefruit or grapefruit juice Hope the explanation given above would be useful to you. A feed back is appreciated.