My sister is battling a depression. The doc put her on trazodone and has increased the dose a couple of times, but she doesn t seem to improve. When I talked to her about it, she said the doc keeps on telling her to trust him and the treatment. I know she s never been keen on pills, taking them as last resort only for about anything and I also know she started by fighting the doc on this and not wanting the pills. Last time we spoke, she was pretty down and said that if the pills are so good, then she might as well take a box full of them at once to become ok. I don t really think she meant it, but what would happen if she actually did so? What if she does take a large amount of pills at once?