The VA is switching me from bupropion to sertraline and am finding that I am nearly impotent without viagra and cannot ejaculate. I also use busporin. The switch is because the nurse practitioner thinks I have built up a tolerance to the bupropion. I had gone in at my wife's behest because she thinks I am acting poorly again. She is right. I am 69 and in generally good health for my age otherwise. Thank you.