Hi, I am sorry to hear you are having these issues after liver transplantation. The goal of liver transplant is to restore a normal life style to patients who would be otherwise very debilitated due to liver failure. One of the major factors which affects recovery after liver transplant is how sick you were before the transplant . If you were bed ridden before transplant, then it takes that much longer after transplant to regain normal body strength as all the muscles would have become weak. Intensive physiotherapy regimens are normally instituted for these patients so that they become completely functional again. Added to this, there are a lot of medications, which the patient has to take, which decreases appetite and also which have potential to cause decreased blood cell counts. This could in turn cause weakness. Also since the immune system is suppressed after a transplant, infections are very common which can again lead to weakness. In your case, it has been more than 5 years since your transplant. It is unlikely that any infection or drug effects are the cause of weakness. Provided your liver function tests are normal, I would also suggest getting your heart and lungs checked as the most common symptom of any dysfunction is weakness. I am pretty sure that your transplant program has already looked into these treatable causes. If all systems are normal, then the only thing I would suggest is to gradually increase your exercise tolerance by adhering to a exercise regimen. Hope this helped and hope you get well soon.