Hi, I have MS, and am struggling with incontinence issues. I tried Myrbetriq, which did not work at all. Now, I am taking Detrol and it helps. Still, I have urgency very frequently, and I can only sleep about 5 hours at night, before the bladder calls. I also experience intense sharp pain at the urethra, mostly in the morning. Do you think Botox would be a good option?