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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For Severe Pain In Joints When Suffering From Charcot Joint

I had in crarcot in my left foot in November of last year I was in a cast for a month.a few days ago I stepped on a cord and hurt the same foot again. I now cant walk on my foot again. the pain is severe. is it possible that the charcot is back again. also in my right foot I bumped my big toe last week is it possible that charcot could be in that foot too.i have severe pain in the joint in that foot also. what should I do
Mon, 1 Feb 2021
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General & Family Physician,  's  Response
Hi,

Charcot joint also called Charcot neuropathic osteoarthropathy. Charcot joint is classified into two types, neuro traumatic and neuro vascular. In neuro traumatic, repeated trauma to the foot and ankle due to neuropathy of the joint results in dislocation and fracture of the joint which ends in deformity. In neuro vascular type, there is increased blood flow to the joint which increases the bone osteoclastic activity that is destruction of the bone because of demineralization.

Diabetes, neuropathy, trauma and metabolic abnormalities are the causes for Charcot joint. Due to the absence of necessary hormones and its related action such as calcitonin gene related peptide which inhibits the cytokine causing inflammation of the joint. Absence of CGRP results in high inflammatory cytokine affecting the joint which in turn causes dislocation and fracture of the joint. CGRP also maintains the integrity of the joint capsule. Imaging studies and metabolic studies helps to confirm the condition and treat the defect earlier to prevent any deformity. Visit the orthopedist for further evaluation and management.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Pradeepraj, General & Family Physician
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Suggest Treatment For Severe Pain In Joints When Suffering From Charcot Joint

Hi, Charcot joint also called Charcot neuropathic osteoarthropathy. Charcot joint is classified into two types, neuro traumatic and neuro vascular. In neuro traumatic, repeated trauma to the foot and ankle due to neuropathy of the joint results in dislocation and fracture of the joint which ends in deformity. In neuro vascular type, there is increased blood flow to the joint which increases the bone osteoclastic activity that is destruction of the bone because of demineralization. Diabetes, neuropathy, trauma and metabolic abnormalities are the causes for Charcot joint. Due to the absence of necessary hormones and its related action such as calcitonin gene related peptide which inhibits the cytokine causing inflammation of the joint. Absence of CGRP results in high inflammatory cytokine affecting the joint which in turn causes dislocation and fracture of the joint. CGRP also maintains the integrity of the joint capsule. Imaging studies and metabolic studies helps to confirm the condition and treat the defect earlier to prevent any deformity. Visit the orthopedist for further evaluation and management. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Pradeepraj, General & Family Physician