Hello! Thank you for asking on HCM! I carefully read your question and would explain that it is important consulting with a doctor for a neurological examination and perform further investigations to establish the possible cause of your headaches. The fact that your headaches have not improved by pain killers raises suspicions of a possible secondary cause of headaches. I would recommend performing these tests: - a brain CT scan to examine your sinuses for possible sinus infection and exclude possible intracranial lesions (tumor, infection, etc.) - blood lab tests (complete blood count for anemia, PCR, sedimentation rate for inflammation). You should discuss with your doctor on the above tests. Hope you will find this answer helpful! Kind regards, Dr. Aida