Hi welcome to HCM I have gone through your query for treatment of pre diabetes . Prediabetes means that your blood sugar level is higher than normal, but it s not yet high enough to be classified as type 2 diabetes. Dear ,your decreasing appetite is matter of concern , but nothing to worry . I suggest you to take balanced regular diet .Include all essential nutrients less carbs , more of fiber,protein , vitamins ,minerals in natural form as juicy fruit ,green leafy veges , spplements full of antioxidants - lemon juice ,bitter gourd juice 25 ml , Aloe vera juice +Amla juice , coconut water , turmeric with a cup of hot milk + a T spoon almond oil, almond a few to count , and proper , exercise regular walk yoga ,pranayam - deep breathing will fulfill your requirement of balanced diet ,and overall detoxification of your system . Avoid fried , fast foods tea ,coffee ,alcohol ,smoking ,mental stress ,worry anxiety and most important is to clear you bowls . as constipation is mother of all ills Last but not the least shun your mental stress , worry ,anger to get sound sleep practice meditation to enhace resistance from diseases and pave way for healthy , happy ,disease free life if above regimen followed regularly . treatment with tablets and insulin is not enough anyway .A strict diet control and regular exercise to control weight is a part of the therapy. Hope this helps you solve your query . Take care .All the best Don t hesitate to come back for further query if any .