i have been suffering for a few years! from itching, and at times, quite severe. It is my taint and lower butt crack next to my taint. It also occurs, but may not be related, at the top of my crack, but more outer part on each side. I have felt that this upper itch may be hemorrhoid related - internal So, these could be two separate situations - or not. I have used Nystatin for a length of time and from time to time Hydrocordisone cream. Also, I was just reading online to try to wash/dry and use Neosporin. I just applied it and am hoping for good results. Also, I had a yeast problem earlier this year and perhaps it is related.???