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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For High BP Despite Taking Losartan/HCTZ

my 21 yr old daughter has HTN she is thin healthy no health problems and her work up age 18 yr renal scan, echo ekg , labs all normal . she has tired lisinopril /hctz help but developed cough then changed to lorsarten/hctz ,terrible control for bp now on diovan /hctz , she is still have bp reading 120/102 best one are 120 92 .I worried we are missing something and wonder what other reason could cause her to have problems possible endocrine this has not been worked up .or should we go to urology thanks Kellie
Fri, 6 Jul 2018
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Cardiologist 's  Response
Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.

I would explain that as all her tests have resulted normal, it could be just primary hypertension. Anyway, I would recommend also checking adrenal gland function if she has not already performed these tests:
- Cortisol and Aldosterone plasma levels
- Urinary metanephrines
- Renine plasma levels

In the meantime, I recommend adding Amlodipine or Lercanidipine to her therapy, in order to help maintain her blood pressure under control.
An abdominal MRI may be needed.
Hope you will find this answer helpful!
Kind regards,
Dr. Iliri
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Suggest Treatment For High BP Despite Taking Losartan/HCTZ

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. I would explain that as all her tests have resulted normal, it could be just primary hypertension. Anyway, I would recommend also checking adrenal gland function if she has not already performed these tests: - Cortisol and Aldosterone plasma levels - Urinary metanephrines - Renine plasma levels In the meantime, I recommend adding Amlodipine or Lercanidipine to her therapy, in order to help maintain her blood pressure under control. An abdominal MRI may be needed. Hope you will find this answer helpful! Kind regards, Dr. Iliri