My friend was prescribed flexerol and tramadol to be taken together for knee pain. He is 72 years old with A-Fib and also has COPD. He had terrible complications from it. Hallucinations, seizures, muscle weakness and confusion. He fell in his garage on concrete, ended up with a large laceration on his shin, which got infected and now he has constant neck pain, arms and shoulders. Not to mention has no strength in his arms or legs. He hurts All of the time. He can not drive due to vertigo. I have been taking him to physical therapy, but it is not helping yet. He had to have a head CT and cervical X-rays. What can he do to get relief? His mental functions have been altered also. He used to be very quick, could remember everything and tell you in detail about it. He can t even remember what he watched on TV. This occurred the first part of June. CT showed moderate diffuse cerebral atrophy and left caudate head and internal capsule infarct.