Hi. Thanks for your query for your diabetic wife suffering from gases and bloating. Alpha-galactosidase helps in breakdown of the complex sugars in terminal colon hence reducing the chances of formation of the gas. It may not increase the blood sugars and you can always keep an eye on the blood sugars and stop it the moment you feel there is increase in blood sugar you can stop it or increase the dosage of Insulin or other medicines. Neomycin itself can be a reason for gas production. I would advise : -Stop all the foods and beverages including carbonated drinks that cause increased problems like bloating and gas formation., -Try another antibiotic with Tinidazole -Reduced stress and anxiety as they do cause aerophagia. -Colonoscopy CT scan of the abdomen to rule out any other problems like cancer. -Movements - ambulation in house .