My fiancee is a 54 year s old male with known dormant hep c, chronic pain, rods in back, past merca, bipolar, manic depression, and a non reversible stoma and has chronic blockage issues. At this time his stoma is raw and bleeding. Severly swollen feet, knees and hands. A large protrusion on his wrist by thumb. That has gotten bigger within past few hours, his hands, feet abd knee have also gotten bigger. He I d refusing to go to hospital. He is in severe pain. I am concerned what should I do? What could be causing these issues?