The suppository is a topical steroid which helps reduce inflammation and hopefully pain.but it is not a direct pain reliever. A fissure is a cut and like any cut it hurts especially hen something like a bowel movement passes it. try to keep your bowel movements soft with stool softeners and sitting in a warm bath may give you some relief. If all fails and the pain continues, ask your doctor for a muscle relaxing ointment because there e is likely spasm of the anal sphincter. The ointment can be a nitrate or calcium channel blocker type of ointment . Your doctor should know about these or refer you to a gastroenterologist.