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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Risk With Water Retention In The Liver In Elderly

my grandmother 75 has suffering from liver problem she has large amount of water in liver. The problem has been from last few 5 months. Doctors of bgh has told that her situation is critical and have no good scope of treatment for this problem. Plz guide me its quite urgent.
Mon, 27 Mar 2017
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Gastroenterologist 's  Response
Hi dear,The problem your mother is having is called ascitis,Ascites, is uasually a late manifestation of cirrhosis of the liver,pathophysiologic mechanisms of ascites include the role of inadequate renal prostaglandin production in the development of the hepatorenal syndrome and the possible role of nitric oxide in the pathogenesis of the renal complications of cirrhosis. The aim of medical therapy is to achieve a negative sodium balance and, consequently, fluid loss. Large-volume paracentesis is safe and effective in the management of tense ascites, but use of diuretic agents should be continued to prevent reaccumulation of ascites. Liver transplantation, transjugular intrahepatic portosystemic shunts, or LeVeen shunts should be considered in selected patients with persistent ascites.

Please share her detailed reports and investigations for further opinion.
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Suggest Risk With Water Retention In The Liver In Elderly

Hi dear,The problem your mother is having is called ascitis,Ascites, is uasually a late manifestation of cirrhosis of the liver,pathophysiologic mechanisms of ascites include the role of inadequate renal prostaglandin production in the development of the hepatorenal syndrome and the possible role of nitric oxide in the pathogenesis of the renal complications of cirrhosis. The aim of medical therapy is to achieve a negative sodium balance and, consequently, fluid loss. Large-volume paracentesis is safe and effective in the management of tense ascites, but use of diuretic agents should be continued to prevent reaccumulation of ascites. Liver transplantation, transjugular intrahepatic portosystemic shunts, or LeVeen shunts should be considered in selected patients with persistent ascites. Please share her detailed reports and investigations for further opinion.