Hello Doctor Rynne. My wife is in her 33 week pregnancy and has been constipated, has not had a bowl movement for 4 days. Considering in the order, giving her prune juice and pitted prunes (she has had these already), possibly next Dulcolax suppositories, possible consider to administer Fleet Enema. While I know this is very uncomfortable for my wife and like to resolve it, want to do it safely as well. Kindly advise. Thank you for your advise Marty