What is he progression of mantle cell lymphoma? My 74 year old husband had only 2 treatments when the oncologist determined the treatment was not working...his platelets were 72 and his WBC was 358,000. They basically told him to go home and die. That was a month ago. He has become steadily weaker. He has an appetite, but cannot eat much at one sitting. He has edema in his feet. He is now complaining of a pain in his upper right quadrant; somewhere around his under arm and radiates to the back of his shoulder blades.We are totally clueless.