Hi, Most of the patients with ITP do well without any complications however its most dangerous complication is bleeding into the brain, which can be fatal which can be prevented by avoiding contact sports. * Choose low-impact activities instead of competitive sports or other high-impact activities to decrease your risk of injury and bleeding. * Avoid certain over-the-counter drugs that can affect platelet function, including aspirin, ibuprofen and the blood-thinning medication warfarin. * Limit your intake of alcohol because consuming alcohol can adversely affect blood clotting. * Watch for signs of infection. If you ve had your spleen removed, be alert for any signs of infection, including fever, and seek prompt treatment. Infections can be more serious in people without spleens. Besides the treatments for ITP can have more risks than the disease itself. The long-term use of steroids can cause serious side effects like: * Osteoporosis * Cataracts * Increased risk of infection * Diabetes and high blood pressure * Peptic ulcer Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Mohammed Taher Ali, General & Family Physician