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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suffering With TB, On Treatment, Has Dark Yellow Spot Growing Under Left Eye. Is It Alarming?

my name is kishan omar , i belong to kanpur,up,india. my elder sister (26 years old) got the infectious disease T.B. , the doctor confirmed her after several tests, so now she is taking medicine properly in time as prescribed by doctor, but from past one week , a dark yellow spot is growing (like seed of sarso) in her left eye, i wanted to know about that, is that the thing to worry about or just the side effect of this disease. also i want to know about the precautions she should take to overcome this disease .
Fri, 4 Oct 2013
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Rheumatologist 's  Response
Hi Mr. Kishan Omar. To discuss and make it easy, i'll brief you in the following sections -
1) Tuberculosis is a very common disease in India, and can be very well cured if the prescribed drugs are taken religiously for an adequate duration of time of around 6-9 months depending on the organ affected. Usually 4 drugs Rifampicin, Isoniazid, Pyrazinamide and Ethambutol are prescribed initially for 2-3 months and then 2-3 drugs are prescribed for another 4-7 months. Side effects of drugs need to be monitored for, the most important of which is hepatitis, which manifests as loss of appetite, abdominal pain and jaundice if severe. So liver function tests need to be monitored frequently especially in the initial few months. And there is no specific precaution to be taken apart from these. Give her a good diet rich in proteins and calories. Pyridoxine 10-20mg/day supplements are essential to prevent side effects of isoniazid.
2) the eye lesion, dark yellow spot which you described is unliely due to the drugs which she takes for tuberculosis and this needs a more detailed description to know where and what it is, which is difficult for a layman to provide. Its better that you consult an Ophthalmologist at Kanpur itself for this.
Hope I have answered your queries. Thank you.
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Suffering With TB, On Treatment, Has Dark Yellow Spot Growing Under Left Eye. Is It Alarming?

Hi Mr. Kishan Omar. To discuss and make it easy, i ll brief you in the following sections - 1) Tuberculosis is a very common disease in India, and can be very well cured if the prescribed drugs are taken religiously for an adequate duration of time of around 6-9 months depending on the organ affected. Usually 4 drugs Rifampicin, Isoniazid, Pyrazinamide and Ethambutol are prescribed initially for 2-3 months and then 2-3 drugs are prescribed for another 4-7 months. Side effects of drugs need to be monitored for, the most important of which is hepatitis, which manifests as loss of appetite, abdominal pain and jaundice if severe. So liver function tests need to be monitored frequently especially in the initial few months. And there is no specific precaution to be taken apart from these. Give her a good diet rich in proteins and calories. Pyridoxine 10-20mg/day supplements are essential to prevent side effects of isoniazid. 2) the eye lesion, dark yellow spot which you described is unliely due to the drugs which she takes for tuberculosis and this needs a more detailed description to know where and what it is, which is difficult for a layman to provide. Its better that you consult an Ophthalmologist at Kanpur itself for this. Hope I have answered your queries. Thank you.